630721

6-氨基吲哚

97%

• 别名: Indol-6-ylamine, NSC 82379
• 经验公式（希尔记法）: C₈H₈N₂
• CAS号: 5318-27-4
• 分子量: 132.16
• MDL號碼: MFCD02093959
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24882337
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: 97%
• 形狀: solid
• mp: 75-79 °C
• 儲存溫度: −20°C
• SMILES 字串: Nc1ccc2cc[nH]c2c1
• InChI: 1S/C8H8N2/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H,9H2
• InChI 密鑰: MIMYTSWNVBMNRH-UHFFFAOYSA-N

说明

應用

Reactant for preparation of:

• Inhibitors of mammalian target of rapamycin (mTOR ) protein
• Inhibitors of the AcrAB-TolC efflux pump
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
• Potent DNA-topoisomerase II poisons and anti-MDR agents
• Protein kinase C θ (PKCθ) inhibitors
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists
• Allosteric enhancers of the A3 adenosine receptor
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H315,H319,H335
• 防範說明: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves