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B103608

Sigma-Aldrich

γ-丁内酯

ReagentPlus®, ≥99%

别名:

γ-羟基丁酸内酯, 4-羟基丁酸内酯, GBL

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About This Item

经验公式（希尔记法）:
C4H6O2
CAS号:
96-48-0
分子量:
86.09
Beilstein:
105248
EC號碼:
202-509-5
MDL號碼:
MFCD00005386
分類程式碼代碼:
12352100
PubChem物質ID:
24891553
NACRES:
NA.22

蒸汽密度

3 (vs air)

蒸汽壓力

1.5 mmHg ( 20 °C)

產品線

ReagentPlus®

化驗

≥99%

形狀

liquid

自燃溫度

851 °F

expl. lim.

16 %

折射率

n20/D 1.436 (lit.)

bp

204-205 °C (lit.)

mp

−45 °C (lit.)

密度

1.12 g/mL at 25 °C (lit.)

SMILES 字串

O=C1CCCO1

InChI

1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2

InChI 密鑰

YEJRWHAVMIAJKC-UHFFFAOYSA-N

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相关类别

應用

用于引入3-羧丙基侧链。用作电池和电容器中电解质溶液的组成成分。

生化／生理作用

γ-羟基丁酸(GHB)前体。 可通过阻断多巴胺能神经元的脉冲流，抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

CorrosionExclamation mark
GHS05,GHS07

訊號詞

Danger

危險聲明

H302,H318,H336

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

208.4 °F - closed cup

閃點（°C）

98 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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分析证书(COA)

Lot/Batch Number
STBK8622
STBK6651
STBK6169
STBK2578
STBK0998

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Journal of Power Sources, 43, 195-195 (1993)
S Ohkawa et al.
Journal of medicinal chemistry, 34(1), 267-276 (1991-01-01)
A novel series of (3-pyridylmethyl)benzoquinone derivatives was molecular designed and synthesized for the dual purpose of inhibiting thromboxane A2 and leukotriene biosynthesis enzymes and scavenging active oxygen species (AOS). They were evaluated for inhibition of TXA2 synthase, inhibition of 5-lipoxygenase
Monica Blichowski et al.
Epilepsia, 56(7), 1081-1087 (2015-06-03)
Infantile spasms (or IS) is a catastrophic childhood epilepsy that is particularly prevalent in children with Down syndrome. Previously, we have shown that the Ts65Dn (Ts) mouse model of Down syndrome is a useful substrate upon which to develop an
Jagan N Thupari et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9498-9502 (2002-06-13)
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an alpha-methylene-gamma-butyrolactone, reduces adipose tissue and fatty liver, despite high levels of malonyl-CoA. To investigate this
Tezcan Guney et al.
Organic letters, 15(3), 613-615 (2013-01-18)
The total synthesis of paracaseolide A, a valuable cell-cycle progression inhibitor, was accomplished in 8 steps from known compounds, with 6.6% overall yield. The synthetic strategy creates strong potential for diversification.
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