913979

Biotin-Thalidomide

≥95%

• 别名: N¹-(4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-N⁵-(15-oxo-19-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-14-azanonadecyl)glutaramide, Biotin-conjugated thalidomide, bio-Thal
• 经验公式（希尔记法）: C₄₄H₆₄N₈O₁₃S
• CAS号: 2230857-87-9
• 分子量: 945.09
• MDL號碼: MFCD32851674
• 分類程式碼代碼: 12352200
• NACRES: NA.22

属性

• ligand: thalidomide
• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder
• 儲存溫度: −20°C
• SMILES 字串: O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3OCC(NCCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@](NC(N5)=O)([H])[C@]5([H])CS4)=O)=O)=O)=O)=O)NC1=O
• InChI: 1S/C44H64N8O13S/c53-34(12-2-1-11-33-40-30(28-66-33)49-44(61)51-40)46-19-7-21-62-23-25-64-26-24-63-22-8-20-47-36(55)14-6-13-35(54)45-17-3-4-18-48-38(57)27-65-32-10-5-9-29-39(32)43(60)52(42(29)59)31-15-16-37(56)50-41(31)58/h5,9-10,30-31,33,40H,1-4,6-8,11-28
• InChI 密鑰: UCTZYEDSVDZJQR-NTZPKYJMSA-N

说明

應用

Biotin-Thalidomide (bio-Thal) is a cereblon affinity probe for PROTAC^® and targeted protein degradation research. Bio-Thal can be used in cereblon (CRBN) binding and displacement assays for protein degrader validation experiments, CRBN ligand discovery, competition analyses, or where enrichment of CRBN complexes is required.

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其他說明

The dTAG system for immediate and target-specific protein degradation

法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable