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Merck
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文件

764213

Sigma-Aldrich

生物素-PEG4-炔

for copper catalyzed click labeling

别名:

乙炔-PEG4-生物素结合物

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About This Item

经验公式（希尔记法）:
C21H35N3O6S
CAS号:
1262681-31-1
分子量:
457.58
分類程式碼代碼:
12161502
PubChem物質ID:
329767107
NACRES:
NA.22

化驗

95%

形狀

solid

反應適用性

reaction type: click chemistry

mp

55-64 °C

儲存溫度

−20°C

SMILES 字串

O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O

InChI

1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1

InChI 密鑰

SKMJWNZZFUDLKQ-QWFCFKBJSA-N

相关类别

應用

生物素-PEG4-炔可以通过生物正交叠氮-炔加成反应对 4-叠氮苯丙氨酸 (AzPhe) 丝素蛋白进行改性，以制备光敏性蛋白质材料。
生物素化试剂，采用铜催化的 1，3 偶极环加成点击化学标记含炔烃的分子或生物分子。炔烃基团与叠氮化物反应形成稳定的三唑键，有助于将生物素引入目标炔烃改性体系。

凭借Synple 全自动合成平台（SYNPLE-SC002）自动标记您的生物素

其他說明

肠道微生物群相关胆盐水解酶活性的化学蛋白组学分析

荧光异遥爪单链聚合物纳米颗粒：合成、光谱学和细胞成像

精氨酸选择性化学标记方法，鉴定和富集蛋白中反应性精氨酸残基

选择性成像小鼠肠道中革兰氏阴性菌和革兰氏阳性菌

炔烃唾液酸的代谢寡糖工程，赋予神经氨酸酶抗性，抑制流感病毒繁殖

单细胞水平上，药物定位、目标识别和目标占有率测量的模块化探针策略

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Copper-mediated coupling between alkynes to generate a structurally rigid, linear 1,3-diyne linkage has been known for over a century. However, the mechanistic requirement to simultaneously maintain CuI and an oxidant has limited its practical utility, especially for complex functional molecules
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