品質等級
形狀
solid
反應適用性
reaction type: click chemistry
reagent type: cross-linking reagent
mp
149-157 (decomposition)
官能基
NHS ester
儲存溫度
−20°C
SMILES 字串
O=C(CCC(ON(C(CC1)=O)C1=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
InChI
1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2
InChI 密鑰
XCEBOJWFQSQZKR-UHFFFAOYSA-N
一般說明
DBCO-NHS 酯常用于生物偶联。它由NHS酯组成，NHS酯可以与生物分子上的伯胺和炔基反应，该炔基导致与含叠氮化物分子的特异性反应。该反应通过一种称为应变促进炔烃-叠氮化物环加成的无铜点击化学过程进行。
應用
二苯并环辛炔- N -羟基琥珀酰亚胺酯常用于：
- 通过将DBCO基团引入其表面进行抗体和链霉亲和素等生物分子的修饰和标记
- 作为交联剂使抗原在聚乳酸-乙醇酸共聚物（PLGA）的表面结合。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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商品
Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.
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