754218

3,3-二甲基-1-(三氟甲基)-1,2-苯并碘氧杂戊环

98%

• 别名: 1,3-二氢-3,3-二甲基-1-(三氟甲基)-1,2-苯并碘氧杂戊环, Togni 试剂
• 经验公式（希尔记法）: C₁₀H₁₀F₃IO
• CAS号: 887144-97-0
• 分子量: 330.09
• MDL號碼: MFCD10567056
• 分類程式碼代碼: 12352101
• PubChem物質ID: 329766407
• NACRES: NA.22

属性

• 化驗: 98%
• 形狀: powder
• mp: 75-79 °C
• 儲存溫度: 2-8°C
• SMILES 字串: CC1(C)O[I](c2ccccc12)C(F)(F)F
• InChI: 1S/C10H10F3IO/c1-9(2)7-5-3-4-6-8(7)14(15-9)10(11,12)13/h3-6H,1-2H3
• InChI 密鑰: HVAPLSNCVYXFDQ-UHFFFAOYSA-N

说明

應用

• Selective trifluoromethylation of 1,3-disubstituted arenes through iridium-catalyzed arene borylation and copper-catalyzed trifluoromethylation
• Copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with electrophilic trifluoromethylating reagent
• Pd-catalyzed electrophilic ortho-trifluoromethylation of arenes using trifluoroacetic acid as a promotor

Used in the Preparation of

• Trifluoromethylimidoylethyl substituted heterocycles via bis(trifluoromethylsulfonyl)amine-catalyzed Rotter type reaction of heterocycles with nitriles in presence of trifluoromethylbenziodoxole
• Stereoselective synthesis of α-trifluoromethyl aldehydes via trimethylbenzylimidazolidinone and copper-catalyzed enantioselective α-trifluoromethylation of aldehydes with iodonium salts

安全信息

• 象形圖: GHS02,GHS07
• 訊號詞: Warning
• 危險聲明: H228,H315,H319,H335
• 防範說明: P210 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 4.1B - Flammable solid hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable