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Merck
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732613

Sigma-Aldrich

聚乙二醇甲基醚

average MN 20,000, methoxy, hydroxyl

别名:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

线性分子式:
CH3(OCH2CH2)nOH
CAS号:
9004-74-4
MDL號碼:
MFCD00084416
分類程式碼代碼:
12162002
NACRES:
NA.23

product name

聚乙二醇甲基醚, average Mn 20,000

蒸汽密度

>1 (vs air)

蒸汽壓力

0.05 mmHg ( 20 °C)

形狀

powder or crystals

分子量

average Mn 20,000

mp

64-69 °C

Mw/Mn

≤1.2

Ω-end

hydroxyl

α-end

methoxy

儲存溫度

−20°C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI 密鑰

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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應用

  • Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C.：开发脱氧胆酸接枝的PEG化壳聚糖胶束用于有效递送丝裂霉素C，说明PEG化物质在药物制剂和药物传输系统中的应用前景(Zhang et al., 2015)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

359.6 °F

閃點（°C）

182 °C

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Robert K Delong et al.
Nanomedicine (London, England), 7(12), 1851-1862 (2012-09-05)
Nanoparticle conjugates have the potential for delivering siRNA, splice-shifting oligomers or nucleic acid vaccines, and can be applicable to anticancer therapeutics. This article compares tripartite conjugates with gold nanoparticles or synthetic methoxypoly(ethylene glycol)-block-polyamidoamine dendrimers. Interactions with model liposomes of a
Smita K Pawar et al.
International journal of pharmaceutics, 436(1-2), 183-193 (2012-06-23)
Efficacy of anticancer drug is limited by the severe adverse effects induced by drug; therefore the crux is in designing delivery systems targeted only to cancer cells. Toward this objectives, we propose, synthesis of poly(ethylene glycol) (PEG)-doxorubicin (DOX) prodrug conjugates
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
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