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Merck

95172

Sigma-Aldrich

聚(乙二醇)

BioUltra, 20,000

别名:

PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL號碼:
分類程式碼代碼:
12352104
PubChem物質ID:
NACRES:
NA.26

品質等級

產品線

BioUltra

形狀

flakes

分子量

Mr ~16000-24000

雜質

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

pH值

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

63-66 °C

溶解度

H2O: 50 mg/mL at 25 °C, clear, colorless

負離子痕跡

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

正離子痕跡

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

&lambda ;

50 mg/mL in H2O

紫外吸收

λ: 260 nm Amax: 0.15
λ: 280 nm Amax: 0.20

SMILES 字串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般說明

聚乙二醇(PEG)是一种聚醚化合物,用于作为化妆品,药品及食品的添加剂。它包含重复的乙二醇[-(CH2CH2O)n]单元。

應用

聚乙二醇被用于水分散体系中的非吸附性高分子或作为活性自组装凝胶通过排空相互作用刺激纤维束的形成。

生化/生理作用

聚乙二醇(PEG)是一种合成高分子,被用作生物偶联和纳米药物延长血液循环时间,提高药物疗效的金标准。PEG-偶联药物被认为可在人体上安全使用,并得到美国食品和药品监督局(FDA)批准。PEG在许多生物医学应用,包括生物传感器,成像和组织工程。它还排斥蛋白质吸附和降低肝脏摄取,这有助于包裹纳米颗粒。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Thai Thanh Hoang Thi et al.
Polymers, 12(2) (2020-02-07)
Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles
Pau Guillamat et al.
Science advances, 4(4), eaao1470-eaao1470 (2018-05-10)
The formation of emulsions from multiple immiscible fluids is governed by classical concepts such as surface tension, differential chemical affinity and viscosity, and the action of surface-active agents. Much less is known about emulsification when one of the components is
Wei-An Wang et al.
Soft matter, 15(44), 9111-9119 (2019-11-02)
The diversity of functions achieved by living cells result from the collective behavior of biological components that interact through multiple scales in time and space. The cytoskeleton constitutes one canonical system forming dynamic organizations when interacting with molecular motors. These
Pau Guillamat et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(20), 5498-5502 (2016-05-04)
Living cells sense the mechanical features of their environment and adapt to it by actively remodeling their peripheral network of filamentary proteins, known as cortical cytoskeleton. By mimicking this principle, we demonstrate an effective control strategy for a microtubule-based active
Anisha A D'souza et al.
Expert opinion on drug delivery, 13(9), 1257-1275 (2016-04-28)
Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development. The unique

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