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202495

Sigma-Aldrich

聚乙二醇甲基醚

average MN 750, methoxy, hydroxyl

别名:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

线性分子式:
CH3(OCH2CH2)nOH
CAS号:
9004-74-4
MDL號碼:
MFCD00084416
分類程式碼代碼:
12162002
PubChem物質ID:
24852093
NACRES:
NA.23

产品名称

聚乙二醇甲基醚, average Mn 750

蒸汽密度

>1 (vs air)

蒸汽壓力

0.05 mmHg ( 20 °C)

形狀

paste
solid

分子量

average Mn 750

折射率

n20/D 1.459

黏度

10.5 cSt(210 °F)(lit.)

轉變溫度

Tm 30 °C

密度

1.094 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methoxy

SMILES 字串

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI 密鑰

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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應用

聚（乙二醇）甲基醚可用作：
  • 一种链转移剂，以通过金属开环寡聚反应合成两亲性嵌段共聚物。
  • 作为一种前体，用于制备视甲酸-聚乙二醇纳米组装体，以作为一种高效的药物给药系统
  • 制备与聚乳酸结合的双嵌段共聚物，并将其应用于组织工程和给药领域

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

359.6 °F - closed cup

閃點（°C）

182 °C - closed cup

個人防護裝備

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCJ4912
MKBX5833V
MKBR8584V
MKBK5064V
MKBF8451V

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Yi Wei et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13984-13992 (2012-09-04)
The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
Lina Du et al.
Anti-cancer drugs, 24(2), 172-180 (2012-09-20)
A functionalized poly(amidoamine) (PAMAM) nanocarrier was designed and prepared to deliver anticancer drugs. The nanocarrier is a copolymer with a core-shell structure with 3.0 G PAMAM as the core and sequentially conjugated poly(2-(N,N-diethylamino)ethyl methacrylate) (pDEA) and methoxy-poly(ethylene glycol) 2000 (mPEG)
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