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47674

Sigma-Aldrich

FFmoc-N-三苯甲基-L-谷氨酰胺

≥98.0% (HPLC), for peptide synthesis

别名:

Nα-Fmoc-Nδ-三苯甲基-L-谷氨酰胺

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About This Item

经验公式（希尔记法）:
C39H34N2O5
CAS号:
132327-80-1
分子量:
610.70
Beilstein:
4343953
MDL號碼:
MFCD00077056
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
57651077
NACRES:
NA.26

product name

FFmoc-N-三苯甲基-L-谷氨酰胺, ≥98.0% (HPLC)

品質等級

100

化驗

≥98.0% (HPLC)

形狀

powder

光學活性

[α]/D -14.0±1.5°, c = 1% in DMF

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

應用

peptide synthesis

官能基

Fmoc

儲存溫度

2-8°C

SMILES 字串

OC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46

InChI

1S/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)25-24-35(37(43)44)40-38(45)46-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34/h1-23,34-35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t35-/m0/s1

InChI 密鑰

WDGICUODAOGOMO-DHUJRADRSA-N

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相关类别

一般說明

Fmoc-Gln(Trt)-OH 也称 Nα-Fmoc-Nδ-三苯甲基-L-谷氨酰胺，它是 Fmoc 保护的氨基酸衍生物，可用作合成肽的试剂。 由于谷氨酰胺受到三苯甲基保护，因此可以防止在反应中出现不需要的取代产物。

應用

Fmoc-Gln(Trt)-OH可用作Fmoc 固相肽合成的原料，用于合成fellutamide B 和 fellutamide B的N-辛酰基类似物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

個人防護裝備

Eyeshields, Gloves, type N95 (US)

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
BCCG2426
BCCF4932
BCCC8888
BCCB9522
BCBZ1861

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Serpin proteins irreversibly inhibit serine proteases, but only a small part of the serpin reactive-center loop (RCL) is responsible for the initial protein-protein interaction (PPI). To develop peptidic protease inhibitors, kallikrein-related peptidases 7 (KLK7) and 5 (KLK5) were chosen. Firstly
Marcus Pickhardt et al.
Current Alzheimer research, 14(7), 742-752 (2017-02-06)
Anti-aggregation drugs play an important role in therapeutic approaches for Alzheimer's disease. We have previously developed a number of compounds that are able to inhibit the pathological aggregation of Tau protein. One common obstacle to application is the limited penetration
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Journal of controlled release : official journal of the Controlled Release Society, 242, 35-41 (2016-07-30)
Nanogels offer many unique features rendering them as very attractive candidates for drug delivery. However, for their applications the loading capacity and specific encapsulation, in particular for hydrophobic drugs, in a complex media are two critical factors. In this work
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Macromolecular bioscience, 19(4), e1800410-e1800410 (2018-12-24)
In this paper, a self-delivery chimeric peptide PpIX-PEG8 -KVPRNQDWL is designed for photodynamic therapy (PDT) amplified immunotherapy against malignant melanoma. After self-assembly into nanoparticles (designated as PPMA), this self-delivery system shows high drug loading rate, good dispersion, and stability as
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