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形狀
powder
光學活性
[α]20/D −23°, c = 1 in chloroform
mp
97-99 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](S)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C27H46S/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI 密鑰
QGVQZRDQPDLHHV-DPAQBDIFSA-N
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相关类别
一般說明
硫代胆固醇是一种与胆固醇相似的脂质，但是羟基被巯基取代。
應用
硫代胆固醇用于生物交联 和膜 研究。
也可作为链转移剂 (CTA) 用于 HPMA 单乳酸盐和 HPMA 二乳酸单体的自由基聚合，形成共聚物。[HPMA = N -（2-羟丙基）甲基丙烯酰胺]
也可作为链转移剂 (CTA) 用于 HPMA 单乳酸盐和 HPMA 二乳酸单体的自由基聚合，形成共聚物。[HPMA = N -（2-羟丙基）甲基丙烯酰胺]
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Zhaohua Huang et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 11(3), 409-417 (2005-02-25)
A series of thiocholesterol-based cationic lipids (TCL) has been designed and synthesized by the attachment of thiocholesterol to a cationic amine via a disulfide bond. TCL can be incorporated into liposomes and used to package DNA into a lipoplex, thereby
Biochimica et Biophysica Acta, 691, 24-24 (1982)
Kun Cheng et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 797-805 (2006-02-03)
A triplex-forming oligonucleotide (TFO) specific for type alpha1(I) collagen promoter is a promising candidate for treating liver fibrosis. Earlier, we determined the pharmacokinetics and biodistribution of TFO after systemic administration into normal and fibrotic rats. In this study, we conjugated
M Tanaka et al.
Lipids, 30(4), 321-325 (1995-04-01)
The effect of thiocholesterol (SH-Chol) on the copper-induced in vitro oxidation of low-density lipoprotein (LDL; 1.019 < d < 1.063) was investigated. Among the antioxidants tested, including cysteine, glutathione, 2-mercaptoethanol, dithiothreitol, probucol, thiopalmitic acid, and SH-Chol, SH-Chol was the most
Elisabetta Ranucci et al.
Biomacromolecules, 9(10), 2693-2704 (2008-09-11)
Poly(amidoamine) (PAA) networks that are obtained by the use of cystamine as a cross-linking agent in the reaction with 2,2'-dithiodipyridine turn into linear PAAs with dithiopyridyl side groups that easily undergo an exchange reaction with thiocholesterol. The resultant products represent
商品
The TFA-labile Wang resin is a standard support for batch synthesis of peptide acids following the Fmoc-/tBu-protection scheme.
The TFA-labile Wang resin is a standard support for batch synthesis of peptide acids following the Fmoc-/tBu-protection scheme.
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