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Merck

106615

Sigma-Aldrich

2,2-双(羟甲基)丙酸

98%

别名:

Bis-MPA, DMPA®, 二羟甲基丙酸

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About This Item

线性分子式:
(HOCH2)2C(CH3)COOH
CAS号:
分子量:
134.13
Beilstein:
1756385
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

<1 (vs air)

化驗

98%

形狀

solid

mp

189-191 °C (lit.)

溶解度

H2O: soluble
acetone: slightly soluble
benzene: insoluble
methanol: soluble

SMILES 字串

CC(CO)(CO)C(O)=O

InChI

1S/C5H10O4/c1-5(2-6,3-7)4(8)9/h6-7H,2-3H2,1H3,(H,8,9)

InChI 密鑰

PTBDIHRZYDMNKB-UHFFFAOYSA-N

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應用

2,2-双(羟甲基)丙酸用于聚甲基硅氧烷(Si-PUD)改性聚氨酯分散体的合成和表征研究及其与粘土结合的纳米复合材料。2,2-双(羟甲基)丙酸基树枝状大分子在作为顺铂和多柔比星等强效抗癌药物的递送系统以及硼中子俘获疗法和光动力疗法的药剂方面具有很大的应用价值
2,2-双(羟甲基)丙酸通常用作AB2 单体,用于合成超支化(hb)聚合物和树枝状大分子。
以2,2-双(羟甲基)丙酸合成了具有48个羟基的第四代三分枝树枝状大分子
该酸简单衍生后就可通过“点击”叠氮-炔环加成反应来构建树枝状结构。

法律資訊

DMPA is a registered trademark of GEO Specialty Chemicals, Inc.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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First divergent strategy using two AB2 unprotected monomers for the rapid synthesis of dendrimers.
Brauge L, et al.
Journal of the American Chemical Society, 123(27), 6698-6699 (2001)
Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2, 2-bis (hydroxymethyl) propionic acid.
Ihre H and Hult A.
Macromolecules, 31(13), 4061-4068 (1998)
Kazuki Fukushima et al.
Biomaterials science, 7(6), 2288-2296 (2019-04-25)
Cationic aliphatic polycarbonates bearing primary ammonium side chains have been developed with relatively high molecular weights and controlled macromolecular architectures. These polycarbonates exhibit reasonable antimicrobial activity against Gram-negative and Gram-positive bacteria. The prepared homopolymers could be effective against Gram-negative bacteria
Structure buildup in hyperbranched polymers from 2, 2-bis (hydroxymethyl) propionic acid.
Magnusson H, et al.
Macromolecules, 33(8), 3099-3104 (2000)
Hui Dong et al.
Nanotechnology, 29(5), 055705-055705 (2017-12-13)
Amine-modified amphiphilic hyperbranched polymers (MePEG-H104-Nx) were prepared from hyperbranched 2,2-bis(methylol)propionic acid polyester (H104) by decoration with polyethylene glycol monomethyl ether (MePEG) and different classes of oligo(ethylenimine)s. By using the MePEG-H104-Nx polymers as stabilizers, gold nanoparticles (AuNPs) were prepared in an

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