- Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas.
Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas.
Radiation oncology (London, England) (2017-11-11)
Christin Glowa, Peter Peschke, Stephan Brons, Oliver C Neels, Klaus Kopka, Jürgen Debus, Christian P Karger
PMID29121984
ABSTRACT
To summarize the research activities of the "clinical research group heavy ion therapy", funded by the German Research Foundation (DFG, KFO 214), on the impact of intrinsic tumor characteristics (grading, hypoxia) on local tumor control after carbon ( Three sublines of syngeneic rat prostate tumors (R3327) with various differentiation levels (highly (-H), moderately (-HI) or anaplastic (-AT1), (diameter 10 mm) were irradiated with 1, 2 and 6 fractions of either Experimental results revealed (i) a smaller variation of the TCD The dose-response studies revealed a higher efficacy of
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