Skip to Content
MilliporeSigma

Efficacy of trans-cinnamaldehyde against Psoroptes cuniculi in vitro.

Parasitology research (2012-02-22)
Fengge Shen, Mingxun Xing, Lihui Liu, Xudong Tang, Wei Wang, Xiaohong Wang, Xiuping Wu, Xuelin Wang, Xinrui Wang, Guangming Wang, Junhui Zhang, Lei Li, Jiyu Zhang, Lu Yu
ABSTRACT

The acaricidal activity of trans-cinnamaldehyde was evaluated in vitro on Psoroptes cuniculi. In this study, different concentrations of trans-cinnamaldehyde were tested, and the observed mites mortality was compared with that observed in untreated and treated (Acacerulen R®) controls. The morphological changes in P. cuniculi treated with trans-cinnamaldehyde were examined with light microscopy. By the analysis of variance one-way test, up to 8 μg/ml of trans-cinnamaldehyde gave highly significant (P < 0.01) percentages of mite mortality compared with the untreated controls, but only up to 256 μg/ml, it showed the same efficacy of Acacerulen R®. At the same time, a bioassay was conducted by exposing mites to varying doses of trans-cinnamaldehyde in vitro cultures. The resulting data were analyzed by using a time-dose-mortality modeling technique, yielding the parameters for time and dose effects of P. cuniculi. The β value was 2.01, indicating that trans-cinnamaldehyde had a good activity to kill P. cuniculi adults. Based on the time-dose-mortality relationships fitted and the virulence indices estimated, trans-cinnamaldehyde is a promising microbial agent for mites control.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cinnamaldehyde, natural, ≥95%, FG
Sigma-Aldrich
trans-Cinnamaldehyde, FCC, FG
Supelco
trans-Cinnamaldehyde, analytical standard
Sigma-Aldrich
trans-Cinnamaldehyde, ≥99%
Sigma-Aldrich
trans-Cinnamaldehyde, 97%