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Fatal fulminant hepatic failure due to cyproterone acetate.

Digestive diseases and sciences (1999-09-18)
G Friedman, E Lamoureux, A H Sherker
ABSTRACT

Cyproterone acetate is a normally well-tolerated drug that is used widely for the treatment of prostatic carcinoma. Liver toxicity due to its use is not well known. We describe two cases of fatal fulminant hepatitis related to the use of cyproterone acetate.

MATERIALS
Product Number
Brand
Product Description

Cyproterone acetate for peak identification, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Cyproterone acetate, ≥98%
Cyproterone acetate, European Pharmacopoeia (EP) Reference Standard