Synthesis of nucleoside-based antiviral drugs in ionic liquids.

Synthesis of nucleoside-based antiviral drugs in ionic liquids.

Bioorganic & medicinal chemistry letters (2008-09-18)

Vineet Kumar, Sanjay V Malhotra

ABSTRACT

Nucleoside-based antiviral drugs have been synthesized using imidazolium-based ionic liquids as reaction medium. The ionic liquids were proved to be better solvents for all the nucleoside in terms of solubility and reaction medium as compared to conventional molecular solvents.

MATERIALS

Product Number

Brand

Product Description

B9647

Sigma-Aldrich

(E)-5-(2-Bromovinyl)-2′-deoxyuridine