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Design of selective Cathepsin inhibitors.

Bioorganic & medicinal chemistry letters (2009-07-21)
Paul A Bethel, Stefan Gerhardt, Emma V Jones, Peter W Kenny, Galith I Karoutchi, Andrew D Morley, Keith Oldham, Neil Rankine, Martin Augustin, Stephan Krapp, Hannes Simader, Stefan Steinbacher
ABSTRACT

A number of molecular recognition features have been exploited in structure-based design of selective Cathepsin inhibitors.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
1-Methyl-1H-pyrazole-5-boronic acid pinacol ester, 97%
Sigma-Aldrich
1-Boc-pyrazole-4-boronic acid pinacol ester, 97%