1457902

Nefazodone hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride, BMY-13754, MJ-13754-1, Serzone
• Empirical Formula (Hill Notation): C₂₅H₃₂ClN₅O₂ · HCl
• CAS Number: 82752-99-6
• Molecular Weight: 506.47
• MDL number: MFCD00935760
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750537
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: nefazodone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl
• InChI: 1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H
• InChI key: DYCKFEBIOUQECE-UHFFFAOYSA-N
• Gene Information: human ... HTR2A(3356) , HTR2C(3358) , SLC6A2(6530) , SLC6A4(6532)

Description

Application

Nefazodone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Nefazodone Hydrochloride Tablets

Biochem/physiol Actions

Novel antidepressant; mixed 5-HT_2A serotonin receptor antagonist/serotonin uptake inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable