1202005

Dihydroergotamine mesylate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Dihydroergotamine methanesulfonate salt
• Empirical Formula (Hill Notation): C₃₃H₃₇N₅O₅ · CH₄O₃S
• CAS Number: 6190-39-2
• Molecular Weight: 679.78
• MDL number: MFCD00058615
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749596
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: dihydroergotamine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CS(O)(=O)=O.[H][C@@]12Cc3c[nH]c4cccc(C1C[C@H](CN2C)C(=O)N[C@]5(C)O[C@]6(O)N([C@@H](Cc7ccccc7)C(=O)N8CCC[C@@]68[H])C5=O)c34
• InChI: 1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;1-5(2,3)4/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39);1H3,(H,2,3,4)/t21-,23?,25-,26+,27+,32-,33+;/m1./s1
• InChI key: ADYPXRFPBQGGAH-WVVAGBSPSA-N

Description

Application

Dihydroergotamine mesylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Agonist at vascular serotonin receptors; partial agonist at α-adrenergic and dopamine D₂ receptors; vasoconstrictor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H312 + H332
• pcodes: P261 - P271 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P362 + P364
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable