PHL83525

Morusin

phyproof^® Reference Substance

• Synonym(s): 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)-4H,8H-benzo[1,2-b:3,4-b′]dipyran-4-one, Mulberrochromene
• Empirical Formula (Hill Notation): C₂₅H₂₄O₆
• CAS Number: 62596-29-6
• Molecular Weight: 420.45
• MDL number: MFCD09953814
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• assay: ≥90.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• storage temp.: 2-8°C
• InChI: 1S/C25H24O6/c1-13(2)5-7-17-22(29)21-19(28)12-20-16(9-10-25(3,4)31-20)24(21)30-23(17)15-8-6-14(26)11-18(15)27/h5-6,8-12,26-28H,7H2,1-4H3
• InChI key: XFFOMNJIDRDDLQ-UHFFFAOYSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Anti-fatigue properties: Morusin is studied for its role in combating fatigue. The research explores its bioguided isolation and bioactivity, suggesting potential applications in health supplements for enhanced physical performance and resilience (Chen et al., 2024).


• Anti-cancer activity in breast cancer: Morusin has been found to inhibit breast cancer-induced osteolysis by targeting the PI3K-mTOR signaling pathway, showcasing its therapeutic potential in cancer treatment (Zhang et al., 2024).


• Aortic valve calcification: Research demonstrates Morusin′s ability to alleviate aortic valve calcification by inhibiting senescence in valve interstitial cells through the Ccnd1/Trim25/Nrf2 axis, highlighting its potential in cardiovascular disease management (Liu et al., 2024).


• Suppression of gastric cancer cell stemness: Morusin is effective in suppressing the stemness characteristics of gastric cancer cells under hypoxic conditions by inhibiting HIF-1α accumulation, providing insights into its use in limiting cancer progression (Chen et al., 2024).


• Chemo-photothermal therapy: A Morusin-Cu(II)-indocyanine green nanoassembly has been developed for cancer therapy, igniting mitochondrial dysfunction and enhancing the therapeutic outcomes of chemo-photothermal treatment strategies (Ran et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable