822881

TOYOPEARL GigaCap^® Q-650S Bulk Media

phase ammonium ion, quaternary, bottle of 25 mL, 35 μm particle size

• Synonym(s): TOYOPEARL GigaCap^® Q-650 Anion Exchange Media
• UNSPSC Code: 41115700

Properties

• product line: TOYOPEARL^®
• form: slurry
• feature: counter ion Cl-
• packaging: bottle of 25 mL
• manufacturer/tradename: Tosoh 22881
• parameter: 3 bar max. pressure
• technique(s): LPLC: suitable
• matrix: hydroxylated methacrylic polymer
• matrix active group: ammonium ion, quaternary phase
• particle size: 35 μm
• operating pH: 3-13
• capacity: >162 g/L adsorption capacity (BSA)
• separation technique: anion exchange

Description

General description

Toyopearl GigaCap Q-650 resin is a high capacity, high resolution anion exchange resin* optimized for the capture and purification of both small and large proteins, including oligonucleotides and monoclonal antibodies. A Toyopearl HW-65 polymeric bead has been chemically modified to provide a higher number of anionic binding sites for increased resin capacity.
Toyopearl GigaCap Q-650M resin exhibits typical dynamic binding capacities in the vicinity of 175 mg/mL for BSA and 49 mg/mL for thyroglobulin, whereas, Toyopearl GigaCap Q-650S has dynamic binding capacities approaching 190 g/L for bovine serum albumin.
Toyopearl GigaCap Q-650 resin maintains high capacity at increased linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The high capacity, combined with the 35 μm mean particle size, makes Toyopearl GigaCap Q-650S ideal for high resolution applications.
In addition to the high DBC and good pressure flow characteristics, Toyopearl GigaCap Q-650 resin displays excellent binding and elution kinetics, which results in a more concentrated protein fraction collected during the elution step.
*specifically designed for packed bed use

Specifications

Clean in place with 0.5 M NaOH or 0.1 M HCl.

Physical form

72% (v/v) slurry in 20% (v/v) ethanol

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Legal Information

Toyopearl is a registered trademark of Tosoh Corporation

Toyopearl GigaCap is a registered trademark of Tosoh Corporation

Safety Information

• pictograms: GHS02
• signalword: Danger
• hcodes: H225
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3