Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

T5125

Sigma-Aldrich

Thimerosal

97.0-101.0% (on dried substance, titration)

Synonym(s):

2-(Ethylmercuriomercapto)benzoic acid sodium salt, Ethylmercurithiosalicylic acid sodium salt, Mercury-([o-carboxyphenyl]thio)ethyl sodium salt, Sodium ethylmercurithiosalicylate

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
2-(C2H5HgS)C6H4CO2Na
CAS Number:
54-64-8
Molecular Weight:
404.81
Beilstein/REAXYS Number:
8169555
EC Number:
200-210-4
MDL number:
MFCD00013062
UNSPSC Code:
51473202
PubChem Substance ID:
24900257
NACRES:
NA.21

Quality Level

200

assay

97.0-101.0% (on dried substance, titration)

form

powder or crystals

color

white to faint beige

mp

234-237 °C (dec.) (lit.)

solubility

1 g/L at 20 °C

mode of action

enzyme | inhibits

storage temp.

room temp

SMILES string

[Na+].CC[Hg]Sc1ccccc1C([O-])=O

InChI

1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2

InChI key

RTKIYNMVFMVABJ-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na++K+ dependent ATPases.

Features and Benefits

  • Meets USP/EP testing specifications
  • High-quality chemical, suitable for a wide variety of research applications.

Other Notes

As part of the corporation global plan to support the Minamata Convention eliminating mercury-containing compounds, as of January 2021 customers will be required to provide an End-Use Declaration. The sales of thimerosal will be restricted for approved applications only, such as preservative in vaccine manufacturing, preservative in eye cosmetics, research use within academia (excluding preservation intent) and as reference material only. The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act , European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
For additional information on our range of Biochemicals, please complete this form.
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

Comparable product

Product No.
Description
Pricing

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

target_organs

Kidney

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rune Ehrenreich Kuhre et al.
Cell metabolism, 29(3), 719-726 (2018-11-20)
Studies on isolated pancreatic islets suggest that neuromedin U (NMU), a brain and gastrointestinal peptide, acts as a decretin hormone, inhibiting glucose-stimulated insulin secretion. We investigated whether this effect could be reproduced in vivo and in isolated perfused rat pancreas. Unlike
Pan-Chyr Yang et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 111(6), 333-339 (2012-07-04)
This study evaluated the immune response elicited by two formulations of an AS03(A)-adjuvanted H5N1 A/Indonesia/05/2005 prepandemic influenza vaccine, developed using manufacturing processes with or without thiomersal. In addition, it also evaluated compliance to the Centre for Biologics Evaluation and Research
Dorota Mrozek-Budzyn et al.
Neurotoxicology and teratology, 34(6), 592-597 (2012-10-17)
Despite the common use of Thimerosal as a preservative in childhood vaccines since the 1930s, there are not many studies on ethylmercury toxicokinetics and toxicodynamics in infants. The knowledge of ethylmercury's potential adverse effects is derived mostly from parallel methylmercury
Alicia Bazzano et al.
American journal on intellectual and developmental disabilities, 117(3), 233-242 (2012-06-22)
Although the assertion of a link between vaccines and autism has been scientifically rejected, the theory continues to be popular and may influence the attitudes of parents of children with autism spectrum disorders. The authors sought to assess how often
Alberto Eugenio Tozzi et al.
Developmental medicine and child neurology, 54(9), 843-848 (2012-05-18)
The aim of this article was to explore the effect of duration of breastfeeding on neurocognitive development. The long-term effect of breastfeeding on neurodevelopment was examined through a battery of neuropsychological tests in 1403 children (693 females, 710 males; mean
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service