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T0895

Sigma-Aldrich

Thymine

suitable for cell culture, BioReagent

Synonym(s):

2,4-Dihydroxy-5-methylpyrimidine, 5-Methyluracil

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About This Item

Empirical Formula (Hill Notation):
C5H6N2O2
CAS Number:
65-71-4
Molecular Weight:
126.11
Beilstein/REAXYS Number:
117880
EC Number:
200-616-1
MDL number:
MFCD00006026
UNSPSC Code:
12352207
PubChem Substance ID:
24899920
NACRES:
NA.75

biological source

synthetic

product line

BioReagent

assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

mp

~320 °C (dec.) (lit.)

solubility

1 M NaOH: 50 mg/mL, clear to hazy, colorless to faintly yellow

SMILES string

CC1=CNC(=O)NC1=O

InChI

1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

InChI key

RWQNBRDOKXIBIV-UHFFFAOYSA-N

Gene Information

mouse ... Tymp(72962)

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Subhendu Sekhar Bag et al.
The Journal of organic chemistry, 78(2), 278-291 (2012-11-23)
We report the design and synthesis of triazolyl donor/acceptor unnatural nucleosides via click chemistry and studies on the duplex stabilization of DNA containing two such new nucleosides. The observed duplex stabilization among the self-pair/heteropair has been found to be comparable
Stefano Stella et al.
Acta crystallographica. Section D, Biological crystallography, 69(Pt 9), 1707-1716 (2013-09-04)
Transcription activator-like effectors contain a DNA-binding domain organized in tandem repeats. The repeats include two adjacent residues known as the repeat variable di-residue, which recognize a single base pair, establishing a direct code between the dipeptides and the target DNA.
S I Ahmad et al.
Annual review of microbiology, 52, 591-625 (1999-01-19)
For many years it has been known that thymine auxotrophic microorganisms undergo cell death in response to thymine starvation [thymineless death (TLD)]. This effect is unusual in that deprivation of many other nutritional requirements has a biostatic, but not lethal
Cai Shen et al.
Chemical communications (Cambridge, England), 49(5), 508-510 (2012-12-04)
Supramolecular patterns formed by adsorption from a liquid of nucleobase-terminated molecular rods on a graphite surface were investigated by scanning tunneling microscopy.
M Weinfeld et al.
Progress in nucleic acid research and molecular biology, 68, 139-149 (2001-09-14)
The toxic and mutagenic effects of ionizing radiation are believed to be caused by damage to cellular DNA. We have made use of a novel immunoassay for thymine glycol to examine the removal of this lesion from the DNA of
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