SRP6320

FGF-12 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(s): FGF12B, FHF1, Fibroblast growth factor 12
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥90% (SDS-PAGE)
• form: liquid
• mol wt: 22.6 kDa (201 aa, 1-181 aa + His Tag)
• packaging: pkg of 50 μg
• concentration: 1 mg/mL
• UniProt accession no.: P61328
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... FGF12(2257)

Description

General description

FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange. Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Physical form

1 mg/mL in 20 mM Tris pH 7.5, 10% glycerol, 1 mM DTT, 2 mM EDTA.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable