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SML2747

Sigma-Aldrich

Forsythiaside A

≥98% (HPLC)

Synonym(s):

Forsythoside A, 2-(3,4-Dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]-β-D-glucopyranoside, Forsythiaside

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About This Item

Empirical Formula (Hill Notation):
C29H36O15
CAS Number:
Molecular Weight:
624.59
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -25 to -17°, c = 1 in methanol

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

InChI

1S/C29H36O15/c1-13-22(35)23(36)25(38)29(42-13)41-12-20-27(44-21(34)7-4-14-2-5-16(30)18(32)10-14)24(37)26(39)28(43-20)40-9-8-15-3-6-17(31)19(33)11-15/h2-7,10-11,13,20,22-33,35-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29+/m0/s1

InChI key

DTOUWTJYUCZJQD-UJERWXFOSA-N

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Biochem/physiol Actions

Forsythiaside A is a most abundant phenylethanoid glycosides isolated from Forsythia suspense that exhibits anti-inflammatory and neuroprotective activities. It appears that forsythoside A exerts antipyretic activities through inhibition of transient receptor potential vanilloid 1 (TRPV1) channel.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Quan-Jiang Song et al.
PloS one, 11(9), e0162791-e0162791 (2016-09-13)
Bovine viral diarrhea virus (BVDV), the causative agent of bovine viral diarrhea/mucosal disease (BVD/MD), is an important pathogen of cattle and other wild animals throughout the world. BVDV infection typically leads to an impaired immune response in cattle. In the
Jin Qian et al.
European journal of pharmacology, 812, 250-255 (2017-07-25)
Forsythiaside A (FSA), an active constituent isolated from the Chinese medicinal herb Forsythia suspensa, has been known to have anti-inflammatory effect. However, the effect of FSA on allergic airway inflammation remains unclear. The aim of this study was to investigate

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