SML2351

Dabigatran etexilate

≥98% (HPLC)

• Synonym(s): N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester
• Empirical Formula (Hill Notation): C₃₄H₄₁N₇O₅
• CAS Number: 211915-06-9
• Molecular Weight: 627.73
• MDL number: MFCD22422841
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(OCCCCCC)NC(C(C=C1)=CC=C1NCC2=NC3=CC(C(N(CCC(OCC)=O)C4=NC=CC=C4)=O)=CC=C3N2C)=N
• InChI: 1S/C34H41N7O5/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43)41(20-18-31(42)45-5-2)29-11-8-9-19-36-29/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44)
• InChI key: KSGXQBZTULBEEQ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Dabigatran etexilate is a prodrug of dabigatran, a nonpeptide direct thrombin inhibitor. Dabigatron is an anticoagulant that functions by directly inhibiting both free and fibrin-bound thrombin. Dabigatron has been shown to prevent strokes in those with atrial fibrillation not caused by heart valve issues.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable