SML1591

Buclizine dihydrochloride

≥98% (HPLC)

• Synonym(s): 1-(p-Chloro-α-phenylbenzyl)-4-(p-tert-butylbenzyl)piperazine, 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-diethylenediamine hydrochloride, 1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-piperazine dihydrochloride, Buclina, Longifene, Posdel, UCB-4445, Vibazine, Vibazine hydrochloride
• Empirical Formula (Hill Notation): C₂₈H₃₃ClN₂ · 2HCl
• CAS Number: 129-74-8
• Molecular Weight: 505.95
• MDL number: MFCD00242700
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825975
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 1 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• InChI: 1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H
• InChI key: SDBHDSZKNVDKNU-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

Biochem/physiol Actions

Buclizine is a piperazine antihistamine and anticholinergic that exerts its antiemetic and antimotion sickness effects.

Histamine H1 receptor antagonist

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3