SML1084

BMS-195614

≥97% (HPLC)

• Synonym(s): 4-[5,6-Dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido] benzoic acid; 4-[[[5,6-Dhydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-benzoic acid, BMS 614, BMS-195614, BMS-614, BMS195614, BMS614
• Empirical Formula (Hill Notation): C₂₉H₂₄N₂O₃
• CAS Number: 182135-66-6
• Molecular Weight: 448.51
• MDL number: MFCD00952209
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825462
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥97% (HPLC)
• form: powder
• color: white to light brown
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: CC1(C)CC=C(C2=CN=C(C=CC=C3)C3=C2)C4=C1C=CC(C(NC5=CC=C(C(O)=O)C=C5)=O)=C4
• InChI: 1S/C29H24N2O3/c1-29(2)14-13-23(21-15-19-5-3-4-6-26(19)30-17-21)24-16-20(9-12-25(24)29)27(32)31-22-10-7-18(8-11-22)28(33)34/h3-13,15-17H,14H2,1-2H3,(H,31,32)(H,33,34)
• InChI key: WGLMBRZXZDAQHP-UHFFFAOYSA-N

Description

Biochem/physiol Actions

BMS-195614 (BMS614) is a potent neutral retinoic acid receptor RARα selective antagonist with an IC₅₀ of 2.5 nM.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable