Skip to Content
MilliporeSigma
All Photos(1)

Documents

SML0690

Sigma-Aldrich

L-161,982

≥98% (HPLC)

Synonym(s):

N-[[4′-[[3-Butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1"-biphenyl]-2-yl]sulfonyl]-3-methyl-2-thiophenecarboxamide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C32H29F3N4O4S2
CAS Number:
147776-06-5
Molecular Weight:
654.72
UNSPSC Code:
12352200
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C32H29F3N4O4S2/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40)

InChI key

MMDNKTXNUZFVKD-UHFFFAOYSA-N

Biochem/physiol Actions

L-161,982 is a potent EP4 receptor antagonist that is selective over all other members of the prostanoid receptor family (Ki values are 0.024, 0.71, 1.90, 5.10, 5.63, 6.74, 19 and 23 μM for human EP4, TP, EP3, DP, FP, IP, EP1 and EP2 receptors respectively.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Prostaglandin E2 synthetic, powder, BioReagent, suitable for cell culture

Sigma-Aldrich

P0409

Prostaglandin E2

Prostaglandin E1 ≥98% (HPLC), synthetic

Sigma-Aldrich

P5515

Prostaglandin E1

Prostaglandin E2 ≥93% (HPLC), synthetic

Sigma-Aldrich

P5640

Prostaglandin E2

Michael B Geary et al.
PloS one, 10(8), e0136351-e0136351 (2015-08-28)
Flexor tendon injuries are a common clinical problem, and repairs are frequently complicated by post-operative adhesions forming between the tendon and surrounding soft tissue. Prostaglandin E2 and the EP4 receptor have been implicated in this process following tendon injury; thus

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service