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Key Documents

SCP0103

Sigma-Aldrich

Caspase Substrate

≥95% (HPLC)

Synonym(s):

Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-AFC, caspase-1 substrate VI

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About This Item

Empirical Formula (Hill Notation):
C39H40N5O11
Molecular Weight:
754.76
UNSPSC Code:
12352202
NACRES:
NA.32

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP1(834)

Amino Acid Sequence

Z-Tyr-Val-Ala-Asp-AFC

Biochem/physiol Actions

Z-Tyr-Val-Ala-Asp-AFC, or Z-YVAD-AFC, is a fluorogenic substrate for caspase-1. The parent tetrapeptide is derived from the cleavage site for pro-interleukin b1, as the minimal sequence that caspase-1 recognizes.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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