SAB5900402

Anti-Monkeypox virus/MPXV M1R Antibody (SAA0283)

• Synonym(s): M1R, Monkeypox virus (MPXV)
• UNSPSC Code: 51111800

Properties

• biological source: mouse
• Quality Level: 100
• recombinant: expressed in CHO cells
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• clone: SAA0283, recombinant monoclonal
• assay: >95% (SDS-PAGE)
• form: liquid
• mol wt: 150 kDa
• species reactivity: monkeypox virus
• concentration: 1 mg/mL
• technique(s): ELISA: 1:2000-1:2000; neutralization: 0.01-10 μg/mL
• color: colorless
• pH: 7.4
• isotype: IgG2a, kappa
• Protein ID accession no.: NP_536507.1
• UniProt accession no.: Q8V502
• shipped in: wet ice
• storage temp.: -65 to -96°C
• target post-translational modification: unmodified

Description

General description

Anti-Monkeypox virus/MPXV M1R Antibody, clone SAA0283, is a recombinant monoclonal antibody composed of two heavy chains and two light chains. It is a type of immunoglobulin G (IgG) antibody, which is the most common type of antibody found in the blood and other bodily fluids of humans and other mammals.


Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

Specificity

Monoclonal Anti-Monkeypox virus/MPXV M1R Antibody, clone SAA0283 is specific to the monkeypox virus and binds to its surface proteins. This binding blocks the virus from entering cells and prevents it from replicating, thus preventing infection.

Application

ELISA,neutralization

Packaging

100µg per vial / 1 mg per vial

Storage and Stability

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable