SAB5702135

Anti-SMG1 Antibody, clone 5N10C7, Rabbit Monoclonal

• Synonym(s): ATX, LIP, SMG1 phosphatidylinositol 3-kinase-related kinase
• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 5N10C7, monoclonal
• form: liquid
• mol wt: 340 kDa
• species reactivity: rat, human, rat
• concentration: 0.75 mg/mL
• technique(s): western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: LIQKNLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYEGWTAWV
• UniProt accession no.: Q96Q15
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... Smg1(23049)

Description

General description

This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 3562-3661 of human SMG1 (Q96Q15).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1