SAB5700465

Anti-Phospho-PRKCQ-T538 antibody produced in rabbit

• Synonym(s): PRKCQ, PRKCT, nPKC-theta
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 67; 74; 81
• species reactivity: human
• concentration: 1.59 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q04759
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr538)
• Gene Information: human ... PRKCQ(5588)

Description

General description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

Immunogen

A synthetic phosphorylated peptide around T538 of human PRKCQ (NP_006248.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable