SAB5700380

Anti-Phospho-GSK3B-Y216 + GSK3A-Y279 antibody produced in rabbit

• Synonym(s): GSK3B, gsk-3β
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 46; 48
• species reactivity: human
• concentration: 3.08 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P49841
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr216/pTyr279)
• Gene Information: human ... GSK3B(2932)

Description

General description

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y216 of human GSK3B (NP_001139628).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable