SAB5700363

Anti-Phospho-NF-kB p65-S536 antibody produced in rabbit

• Synonym(s): CMCU, NF-kB p65, NFKB3, RELA, p65
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 58; 59; 60
• species reactivity: rat, mouse, human
• concentration: 1.11 mg/ml
• technique(s): immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• UniProt accession no.: Q04206
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer536)
• Gene Information: human ... RELA(5970)

Description

General description

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S536 of human NF-kB p65

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable