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Key Documents

SAB5200109

Sigma-Aldrich

Anti-AQP1 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Synonym(s):

Anti-AQP1, Anti-Aquaporin 1, Anti-Water channel protein CHIP29

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 28.5 kDa

species reactivity

mouse, human, rat

concentration

1 mg/mL

technique(s)

indirect immunofluorescence: suitable
western blot: suitable

NCBI accession no.

NP_036910.1

UniProt accession no.

P29972

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Aqp1(25240)

General description

Aquaporin 1 (AQP1) is expressed in the nervous system. The gene ID of the protein is 25240.

Specificity

Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.

Immunogen

N-terminal peptide

Biochem/physiol Actions

Aquaporin 1 (AQP1) aids in transporting water across cell membranes. It also contributes to the migration and proliferation of pulmonary arterial smooth muscle cells.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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E Segura-Anaya et al.
Neuroscience, 285, 119-127 (2014-12-03)
Aquaporin 1 (AQP1) is a member of a family of small, integral membrane water-transporting proteins, which facilitate water movement across cell membranes in response to osmotic gradients. Several papers have studied the expression and function of the AQPs in the
Ning Lai et al.
American journal of respiratory cell and molecular biology, 50(6), 1010-1020 (2013-12-18)
Pulmonary arterial smooth muscle cell (PASMC) proliferation and migration are important contributors to the vascular remodeling that occurs during development of pulmonary hypertension. We previously demonstrated that aquaporin (AQP)1, a member of the water channel family of proteins, was expressed
Y L Yu et al.
Biomaterials, 35(25), 6822-6828 (2014-05-27)
Renal regeneration approaches offer great potential for the treatment of chronic kidney disease, but their availability remains limited by the clinical challenges they pose. In the present study, we used continuous detergent perfusion to generate decellularized (DC) rat kidney scaffolds.
Tomoko Iida et al.
Clinical and experimental nephrology, 18(3), 432-443 (2013-07-19)
Several proteins have been proposed as new urinary biomarkers of kidney injuries, but they are not always capable of identifying the kidney nephron segment that has been injured. Since calbindin 1 protein is exclusively localized in the kidney distal nephron
Dieanira Erudaitius et al.
PloS one, 12(1), e0170442-e0170442 (2017-01-21)
Cancer cell toxicity to therapeutic H2O2 varies widely depending on cell type. Interestingly, it has been observed that different cancer cell types have varying peroxiporin expression. We hypothesize that variation in peroxiporin expression can alter cell susceptibility to therapeutic H2O2
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