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Key Documents

SAB5200105

Sigma-Aldrich

Anti-SCNN1A antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Synonym(s):

Anti-ENaC Alpha, Anti-Scnn1a

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

mol wt

antigen predicted mol wt 85 kDa

species reactivity

rat, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

Q61180

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Scnn1a(25122)

General description

Sodium channel epithelial 1 α subunit (SCNN1A) is one of the subunits of epithelial sodium channels. The gene ID of the protein is 25122.

Specificity

Detects ~85 kDa.

Immunogen

AA46–68 of the rat sequence

Biochem/physiol Actions

Sodium channel epithelial 1 α subunit (SCNN1A) deals with sodium transport in the lungs and kidneys of rats.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

PBS, 50% glycerol, and 0.09% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xin-Peng Duan et al.
Hypertension (Dallas, Tex. : 1979), 73(1), 112-120 (2018-12-21)
The stimulation of β-adrenergic receptor increases thiazide-sensitive NaCl cotransporter (NCC), an effect contributing to salt-sensitive hypertension by sympathetic stimulation. We now test whether the stimulation of β-adrenergic receptor-induced activation of NCC is achieved through activating basolateral Kir4.1 in the distal
Megan M Greenlee et al.
American journal of physiology. Lung cellular and molecular physiology, 305(11), L878-L889 (2013-10-08)
Female sex predisposes individuals to poorer outcomes during respiratory disorders like cystic fibrosis and influenza-associated pneumonia. A common link between these disorders is dysregulation of alveolar fluid clearance via disruption of epithelial sodium channel (ENaC) activity. Recent evidence suggests that
Md Shahrier Amin et al.
Hypertension (Dallas, Tex. : 1979), 54(4), 860-867 (2009-07-29)
To elucidate the role of epithelial sodium channels (ENaCs) and Na(+)-K(+)-ATPase in Na(+) transport by the choroid plexus, we studied ENaC expression and Na(+) transport in the choroid plexus. Lateral ventricle choroid plexuses were obtained from young male Wistar, Dahl

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