SAB4702047

Monoclonal Anti-CD81 APC-Cyanine7 produced in mouse

• Synonym(s): CVID6, S5.7, TAPA1, TSPAN28
• UNSPSC Code: 12352203

Properties

• conjugate: APC-Cy7 conjugate
• Quality Level: 100
• antibody product type: primary antibodies
• clone: M38, monoclonal
• form: buffered aqueous solution
• species reactivity: ( Human), rabbit, ( Cat)
• technique(s): flow cytometry: suitable
• isotype: IgG1
• UniProt accession no.: P60033
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... CD81(975)

Description

General description

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Specificity

The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Immunogen

MOLT-4 (human T-ALL cell line)

Physical form

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preparation Note

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage and Stability

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable