SAB4502822

Anti-SMO antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Gx protein, SMO
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 86 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; western blot: 1:500-1:1000
• NCBI accession no.: Q99835
• UniProt accession no.: Q99835
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SMO(6608)

Description

General description

Anti-SMO antibody detects endogenous levels of total SMO protein.

The SMO (smoothened) gene is mapped to human chromosome 7q32.1. It encodes a protein that belongs to the frizzled family of G protein-coupled receptors. It is a seven transmembrane protein and highly conserved.

Immunogen

The antiserum was produced against synthesized peptide derived from human SMO.

Immunogen Range: 68-117

Biochem/physiol Actions

The SMO (smoothened) gene encodes a protein that mediates hedgehog signaling for embryonic development and to maintain tissue homeostasis. SMO participates in tumor cell proliferation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable