SAB3500901
Anti-ANTHRAX PROTECTIVE ANTIGEN antibody produced in rabbit
affinity isolated antibody
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
bacteria
concentration
1 mg/mL
technique(s)
ELISA: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
General description
Anthrax toxin comprises of protective antigen (PA), lethal factor (LF) and edema factor (EF).
Immunogen
Antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Anthrax protective antigen protein.
Biochem/physiol Actions
B. anthracis liberates toxins that plays a vital role in establishing and maintaining infection.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3500901.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Detection of anthrax protective antigen (PA) using europium labeled anti-PA monoclonal antibody and time-resolved fluorescence.
Stoddard RA, et al.
Journal of Immunological Methods, 408, 78-88 (2014)
Mahtab Moayeri et al.
Current opinion in microbiology, 7(1), 19-24 (2004-03-24)
Anthrax lethal toxin is a multi-functional virulence factor that has evolved to target multiple host functions to allow for optimal establishment of Bacillus anthracis infection. The toxin appears to play a role in all stages of infection, from germination to
Recognition and management of anthrax--an update.
M N Swartz
The New England journal of medicine, 345(22), 1621-1626 (2001-11-13)
K A Bradley et al.
Nature, 414(6860), 225-229 (2001-11-09)
The tripartite toxin secreted by Bacillus anthracis, the causative agent of anthrax, helps the bacterium evade the immune system and can kill the host during a systemic infection. Two components of the toxin enzymatically modify substrates within the cytosol of
Heather M Scobie et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(9), 5170-5174 (2003-04-18)
Bacillus anthracis secretes two bipartite toxins thought to be involved in anthrax pathogenesis and resulting death of the host. The current model for intoxication is that protective antigen (PA) toxin subunits bind a single group of cell-surface anthrax toxin receptors
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