SAB2900202

Anti-CX3CR1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): beta chemokine receptor-like 1, chemokine c-x3-c receptor 1, cmkbrl1, cmkdr1, fkn receptor
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
• UniProt accession no.: P49238
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CX3CR1(1524)

Description

General description

C-X3-C motif chemokine receptor 1 (CX3CR1) is a transmembrane G-coupled chemokine receptor of its ligand, fractalkine. This receptor is expressed on epithelial cells, smooth muscle cells, microglia, monocytic cells and natural killer cells. The gene encoding CX3CR1 is localized on human chromosome 3p21.3 and has five exons.

Immunogen

Synthetic 19 amino acid peptide from 3rd extracellular domain of human CX3CR1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (95%); Marmoset, Mouse, Panda (84%).

Biochem/physiol Actions

C-X3-C motif chemokine receptor 1 (CX3CR1) may be linked to the development of macular degeneration. It also acts as a receptor aiding viral entry.

Features and Benefits

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Physical form

Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable