RAB1754
Human Tryptase beta-2 ELISA
for serum, plasma and cell culture supernatants
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 ng/mL
standard curve range: 2.048-500 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TPSB2(64499)
General description
Tryptase β2 (TPSB2) gene codes for mast cell tryptase β2. It is expressed in whole blood by mast cells and their progenitors. Mast cell βII-tryptase protein is a S1A protease.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Tryptase β2 (TPSB2) can break down the large fibronectin substrate into multiple, smaller peptides ranging in size from approximately 30 to 50 kDa. It can also cleave fibrinogen. TPSB2 is associated with pathological inflammation.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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S A Brooks et al.
Animal genetics, 41 Suppl 2, 16-22 (2010-11-26)
Inflammatory damage to the digital laminae, a structure responsible for suspension of the distal skeleton within the hoof capsule, results in a painful and often life-threatening disease in horses called laminitis. There can be many diverse causes of laminitis; however
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