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Key Documents

PLA0306

Sigma-Aldrich

Goat anti-USP7 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

HAUSP, Herpes virus-associated ubiquitin-specific protease, Herpesvirus-associated ubiquitin-specific protease, TEF1, deubiquitinating enzyme 7, ubiquitin specific protease 7 (herpes virus-associated), ubiquitin thioesterase 7, ubiquitin-specific-processing protease 7

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_003461.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

goat ... USP7(7874)

Immunogen

The epitope recognized by PLA0306 maps to a region between residue 1 to 50 of human Ubiquitin Specific Peptidase 7 using the numbering given in entry NP_003461.1 (GeneID 7874).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 7 (USP7) is a member of this family that has been shown to interact and stabilize p53.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Kathryne E Taylor et al.
Journal of virology, 88(14), 8091-8101 (2014-05-09)
The immediate-early protein ICP0 from herpes simplex virus 1 (HSV-1) plays pleiotropic roles in promoting viral lytic replication and reactivation from latency. Most of the known actions of ICP0 occur in the nucleus and are thought to involve the E3

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