MAK533

Arginase Assay Kit

sufficient for 100 colorimetric tests

• UNSPSC Code: 12161503
• NACRES: NA.84

Properties

• Quality Level: 100
• application(s): pharmaceutical
• detection method: colorimetric
• relevant disease(s): gastrointestinal diseases; neurological disorders
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

Arginase (L-arginine ureohydrolase) is present in mammals and plants. In humans, arginase is expressed predominantly in the liver, and to lesser degrees in breast, kidney, testes, salivary glands, epidermis, and erythrocytes. Arginase catalyzes the conversion of arginine to ornithine and urea, completing the last step in the urea cycle. Arginase activity is a key diagnostic indicator. Increased levels of arginase activity in blood have been associated with liver damage. Hyperargininemia due to arginase deficiency is an inherited autosomal recessive disease.

Features and Benefits

• Detection limit: 0.3 U/L
• Compatible with high-throughput handling systems.

Suitability

The kit is suitable for the determination of arginase activity in enzyme preparations, serum, plasma, tissue culture etc., as well as for studying the effects of drugs on arginase activity.

Principle

The Arginase Assay Kit provides a sensitive and convenient method for arginase activity determination. The method utilizes a chromogen that forms a colored complex specifically with urea produced in the arginase reaction. The intensity of the color is directly proportional to the arginase activity in the sample.

Safety Information

• pictograms: GHS08,GHS05
• signalword: Danger
• hcodes: H290,H314,H360FD,H412
• pcodes: P202 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1A
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable