Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

L1663

Sigma-Aldrich

Lidocaine N-ethyl chloride

Synonym(s):

N-(2,6-Dimethylphenylcarbamoylmethyl) triethylammonium chloride

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C16H27N2OCl
CAS Number:
Molecular Weight:
298.85
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

storage condition

protect from light

Quality Level

solubility

H2O: soluble

storage temp.

room temp

SMILES string

[Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C16H26N2O.ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H

InChI key

LLPPOMUAOGMYQI-UHFFFAOYSA-N

Biochem/physiol Actions

Lidocaine N-ethyl chloride is an intracellular voltage-gated sodium channel blocker.

Other Notes

Stable at room temperature lyophilized. In solution, store at 4 °C for up to two weeks. Store solutions at -20 °C for up to six months.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Vijay K Samineni et al.
Nature communications, 10(1), 4356-4356 (2019-09-27)
Itch is a distinct aversive sensation that elicits a strong urge to scratch. Despite recent advances in our understanding of the peripheral basis of itch, we know very little regarding how central neural circuits modulate acute and chronic itch processing.
Mariana Colino-Oliveira et al.
Purinergic signalling, 12(2), 283-294 (2016-02-22)
Brain-derived neurotrophic factor (BDNF) and adenosine are widely recognized as neuromodulators of glutamatergic transmission in the adult brain. Most BDNF actions upon excitatory plasticity phenomena are under control of adenosine A2A receptors (A2ARs). Concerning gamma-aminobutyric acid (GABA)-mediated transmission, the available
Michael A Freed
The Journal of physiology, 595(22), 6979-6991 (2017-09-16)
Bipolar and amacrine cells presynaptic to the ON sustained α cell of mouse retina provide currents with a higher signal-to-noise power ratio (SNR) than those presynaptic to the OFF sustained α cell. Yet the ON cell loses proportionately more SNR
Iina Korkka et al.
Stem cells translational medicine, 8(2), 179-193 (2018-11-06)
Retinal pigment epithelium (RPE) performs important functions for the maintenance of photoreceptors and vision. Malfunctions within the RPE are implicated in several retinal diseases for which transplantations of stem cell-derived RPE are promising treatment options. Their success, however, is largely
Daniel Müller-Komorowska et al.
Frontiers in neural circuits, 14, 16-16 (2020-05-13)
Transgenic Cre-recombinase expressing mouse lines are widely used to express fluorescent proteins and opto-/chemogenetic actuators, making them a cornerstone of modern neuroscience. The investigation of interneurons in particular has benefitted from the ability to genetically target specific cell types. However

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service