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Key Documents

G9887

Sigma-Aldrich

γ-Globulins from sheep

≥99% (agarose gel electrophoresis)

Synonym(s):

Gamma globulin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

sheep

assay

≥99% (agarose gel electrophoresis)

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤4% NaCl

storage temp.

−20°C

General description

γ-Globulin molecules is made up of four polypeptide chains, of which two have molecular weights of about 50,000 and two of about 20,000. These chains are cross-linked by disulfide bonds.

Application

γ-Globulins from sheep were used to study the influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI. It was used in a study to test the interstitial transport of rabbit and sheep antibodies in normal and neoplastic tissues. It was also used in a study to test the enhanced progesterone and testosterone secretion, and depressed estradiol secretion in vitro from small white follicle cells of incubating turkey hens.

Preparation Note

Prepared from Cohn Fraction II, III

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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M A Clauss et al.
Cancer research, 50(12), 3487-3492 (1990-06-15)
Interstitial transport of fluorescein isothiocyanate-conjugated nonspecific polyclonal rabbit and sheep IgG was studied in normal (mature granulation) and neoplastic (VX2 carcinoma) tissues grown in a rabbit ear chamber. The interstitial concentration gradients after i.v. injection were analyzed to yield effective
T E Porter et al.
General and comparative endocrinology, 74(3), 400-405 (1989-06-01)
This study was conducted to determine if lower steroid secretion by the small white follicles in incubating turkey hens contributes to lower circulating steroid concentrations during this time. Turkey hens were grouped as either laying or incubating. Serum samples and
Thomas J F Nieland et al.
Journal of lipid research, 48(8), 1832-1845 (2007-05-30)
Treatment of atherosclerotic disease often focuses on reducing plasma LDL-cholesterol or increasing plasma HDL-cholesterol. We examined in vitro the effects on HDL receptor [scavenger receptor class B type I (SR-BI)] activity of three classes of clinical and experimental plasma HDL-cholesterol-elevating
[Postoperative thrombosis prevention using low-dose heparin].
A E Schaer et al.
Archiv fur Gynakologie, 219(1-4), 545-545 (1975-11-18)

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