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DMPS5X

Sigma-Aldrich

Dimethylpolysiloxane

viscosity 50 cSt (25 °C)(lit.)

Synonym(s):

Polydimethylsiloxane

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About This Item

CAS Number:
9016-00-6
MDL number:
MFCD00084411
UNSPSC Code:
12352200
PubChem Substance ID:
24894361
NACRES:
NA.25

form

liquid

Quality Level

200

mol wt

~3,780

viscosity

50 cSt(25 °C)(lit.)

InChI

1S/C2H6OSi/c1-4(2)3/h1-2H3

InChI key

SEUDSDUUJXTXSV-UHFFFAOYSA-N

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Application

Dimethylpolysiloxane has been used:
  • in culturing mouse embryos
  • in preparation of oil-based nano-adjuvant candidates
  • to reduce the brain movement in the post-cat craniotomy process

Clear, colorless fluid polymer useful as a stationary phase in gas chromatography and as an anti-foaming agent.

Biochem/physiol Actions

Dimethylpolysiloxane is a silicon-based organic polymer, inert and non-toxic. It is applicable in the pharmaceutical, food, and cosmetic industry. Dimethylpolysiloxane is excreted unchanged unaltered in the faeces and is non-mutagenic.
Dimethylpolysiloxane is used in protein chromatography and affininty chromatography. Dimethylpolysiloxane was used to determine that postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

609.8 °F - closed cup

flash_point_c

321 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificates of Analysis (COA)

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Zengguang Ma et al.
Neuroscience letters, 637, 161-167 (2016-11-20)
Understanding the mechanisms underlying negative hemodynamic responses is critical for the interpretation of functional brain imaging signals. Negative imaging signals have been found in the visual, somatosensory and motor cortices in functional magnetic resonance imaging (fMRI) and intrinsic signal optical
Comparison of cortical responses to the activation of retina by visual stimulation and transcorneal electrical stimulation.
Sun, et al.
Brain Stimulation, 11, 667-675 (2019)
A Perez-Herrera et al.
Molecular nutrition & food research, 56(3), 510-514 (2011-12-14)
Heating during the process of cooking alters the chemical properties of foods and may affect subsequent postprandial inflammation. We tested the effects of four meals rich in different oils subjected to heating on the postprandial inflammatory metabolism of peripheral blood
Vyacheslav N Fishman et al.
Chemosphere, 84(7), 913-922 (2011-07-09)
The applicability of three different Silphenylene Silicone co-polymer (Si-Arylene) GC stationary phases (J&W Scientific DB-5ms, Varian VF-5ms, and VF-Xms) has been evaluated for the separation of all 136 tetra- through the octa- chlorinated dibenzo-p-dioxins (PCDD) and chlorinated dibenzofurans (PCDF) from
Mara I Orozco et al.
Journal of agricultural and food chemistry, 59(13), 7194-7202 (2011-06-08)
The influence of deep frying, mimicked by 20 heating cycles at 180 °C (each cycle from ambient temperature to 180 °C maintained for 5 min), on the unsaponifiable fraction of vegetable edible oils represented by three characteristic families of compounds

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