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D9690

Sigma-Aldrich

β-Defensin 2 human

recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

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About This Item

MDL number:
MFCD01634440
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

form

lyophilized powder (from 10 mM acetic acid)

mol wt

estimated mol wt 4.3 kDa

UniProt accession no.

O15263

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
viruses

mode of action

cell wall synthesis | interferes

storage temp.

−20°C

Gene Information

human ... DEFB4(1673)

Amino Acid Sequence

Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro

General description

Chemical structure: peptide

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity and is expressed in keratinocytes and the epithelia of many organs.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Antimicrobial Peptides

With bacterial resistance and emerging infectious diseases becoming potential threats to humans, ribosomally synthesized antimicrobial peptides have become a promising focus area in antibiotic research.

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