C5259

Carbamyl-β-methylcholine chloride

≥99% (TLC), crystalline

• Synonym(s): Bethanechol chloride
• Linear Formula: C₇H₁₇N₂O₂Cl
• CAS Number: 590-63-6
• Molecular Weight: 196.68
• EC Number: 209-686-8
• MDL number: MFCD00055224
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277823
• NACRES: NA.25

Properties

• Quality Level: 100
• assay: ≥99% (TLC)
• form: crystalline
• color: white
• solubility: H₂O: 1.7 g/mL (stable for several days at 4°C.); ethanol: 80 mg/mL (stable for several days at 4°C.)
• storage temp.: 2-8°C
• SMILES string: Cl.CC(C[N](C)(C)C)OC(N)=O
• InChI: 1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H
• InChI key: AIRHOJQHGLTTTB-UHFFFAOYSA-N

Description

Application

Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay. It has also been used in concentration-response studies with isolated atrial preparation.

Biochem/physiol Actions

Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.

Caution

Hygroscopic.

Substrates

Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves