C277

Chloro-IB-MECA

solid, ≥98% (HPLC)

• Synonym(s): 2-Chloro-N⁶-(3-iodobenzyl)-adenosine-5′-N-methyluronamide, Cl-IB-MECA
• Empirical Formula (Hill Notation): C₁₈H₁₈ClIN₆O₄
• CAS Number: 163042-96-4
• Molecular Weight: 544.73
• MDL number: MFCD01861178
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278354
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: >20 mg/mL
• SMILES string: CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc23
• InChI: 1S/C18H18ClIN6O4/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1
• InChI key: IPSYPUKKXMNCNQ-PFHKOEEOSA-N
• Gene Information: human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140) ; rat ... Adora1(29290) , Adora2a(25369) , Adora3(25370)

Description

Biochem/physiol Actions

2-chloro-N(6)-(3-iodobenzyl)adenosine-5′-N-methylcarboxamide (Cl-IB-MECA) is a adenosine receptor. It protects against myocardial ischemia/reperfusion injury in mice.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves